Herantis Pharma Plc announces topline results of Phase 1-2 CDNF trial Tue, Feb 25, 2020 08:00 CET. Topline analysis confirms positive safety and tolerability of CDNF in advanced-stage Parkinson’s disease patients, with encouraging biological responses as measured by PET imaging in some patients.

Herantis Pharma är ett finländskt läkemedelsutvecklingsbolag som i kliniska studier – CDNF mot Parkinsons och Lymfactin mot lymfödem.

CDNF on Herantiksen yksinoikeudella kehittämä, hermosoluja suojaava lääkeaihio, jonka tavoitteena on muuttaa Parkinsonin taudinkulkua, mikä olisi merkittävä läpimurto verrattuna tunnettuihin In order to do this, Herantis has developed xCDNF, a patented, chemically synthesised form of CDNF that uses small but potent biologically active fragments of the parent CDNF molecule, which it says can reach the key areas of the brain in therapeutic concentrations using a simple dosing method such as subcutaneous injection. Herantis Pharma is focused on the development of innovative regenerative medicines targeting unmet needs. The recent virtual capital markets day highlighted the progress of its two innovative assets: cerebral dopamine neurotrophic factor (CDNF), a potential disease-modifying treatment for Parkinsonâ s disease (PD); and Lymfactin, the only gene therapy in development for breast cancer Herantis Pharma is a Finnish innovative biopharmaceutical company focusing on regenerative medicines for unmet needs. Key assets include CDNF for Parkinson’s disease and Lymfactin for breast cancer associated lymphedema. 2021-03-29 · Herantis Pharma Oyj. Yhtiötiedote, Sisäpiiritieto.

Herantis cdnf

Both CDNF and xCDNF have, via their multimodal mechanism of action, the potential improves neuronal survival and to stop the progression of Parkinson’s and other About CDNF. As opposed to other treatment modalities for Parkinson ’s disease, CDNF represents an opportunity to modify the disease state by alleviating both motor and non-motor symptoms and stopping disease progression; effects that Herantis has demonstrated in non-human primates. About Lymfactin Herantis Pharma Oyj: Herantis Pharma keskittyy CDNF- ja xCDNF-ohjelmiin 2021-03-25 Herantis Pharma Oyj: Herantis Pharma on julkaissut vuoden 2020 vuosikertomuksen 2017-10-02 · Herantis Pharma has started the first clinical trial of cerebral dopamine neurotrophic factor (CDNF) as a potential treatment for Parkinson’s disease. The first patient in the Phase 1/2 clinical trial has enrolled at the Karolinska University Hospital in Stockholm. The study will also involve Herantis has announced top-line data from the first part of the Phase I/II clinical trial on novel asset CDNF in Parkinson’s disease (PD). Data reported for the first six months are preliminary in this first-in-human clinical study for this novel MOA drug class.

2018-02-14 · Herantis Pharma opening recruitment in Parkinson's disease study in Helsinki and Lund based on favorable first CDNF safety assessment. Herantis Pharma Plc Company release 14 February 2018 at 9:00 am.

2019-09-26 · Herantis Pharma Plc Provides Update on Timeline for Ongoing Phase 1-2 CDNF Trial. Herantis Pharma Plc Company release 26 September 2019 at 9:00 AM 2018-07-10 · Herantis Pharma is launching a development program for non-invasive cerebral dopamine neurotrophic factor (CDNF) as a treatment candidate for patients with Parkinson’s disease, the company recently announced. Currently, the investigational treatment needs to be administered directly into the Två så kallade proof of concept studier med Herantis CDNF och xCDNF molekyler ska genomföras. En känd utmaning i läkemedelsvärlden vid behandling av hjärnan är att ta sig förbi blod-hjärnbarriären.

This comes following Herantis' recent pivot away from direct intracerebral delivery for CDNF and towards alternative administration methods, principally intra-nasal

Idag innehas särskilt fokus mot behandling av ett flertal sjukdomar som Parkinsons sjukdom, skleros samt bröstcancer. Bolaget innehar en produktportfölj som för närvarande befinner sig i diverse kliniska faser. 2020-02-25 · Source: Herantis It is cold this time of year in Helsinki, but there will be some warm smiles there today. A small biotech firm called Herantis Pharma has announced the topline results of their Phase 1/2 clinical trial exploring the safety and tolerability of a treatment called CDNF. Herantis announced today the topline results from the ongoing Phase 1-2 clinical trial examining Herantis’ proprietary neuroprotective factor and novel drug candidate, CDNF, in patients with Parkinson’s disease. 2019-08-28 · Herantis has patented CDNF internationally.

With the main study of the Phase I/II cerebral dopamine neurotrophic factor (CDNF) study now complete in Parkinson’s disease (PD) (top-line safety and efficacy data are expected in Q120), positive trial data could validate the research efforts and enable future partnering opportunities.
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Herantis Pharma Oyj: Herantiksen CDNF on turvallinen ja hyvin siedetty Vaiheen 1-2 tutkimuksessa 12 kuukauden hoidon jälkeen. Publicerad: 2020-08-27 (Cision) Herantis Pharma Oyj: Herantis Pharma Plc Announces CDNF Phase I-II Study Met Primary Endpoints of Safety and Tolerability at 12 months. Publicerad: 2020-08-27 (Cision) Herantis Pharma Oyj: NOTICE TO CONVENE HERANTIS PHARMA PLC'S ANNUAL GENERAL MEETING OF SHAREHOLDERS 23 Mar 2021 / Press release; Livestreamed Seminar Today - ABGSC Investor Day 9 March 9 Mar 2021 / Article; Herantis Pharma - H2’20 Report 3 Mar 2021 / Analys Herantis Pharma Plc announces topline results of Phase 1-2 CDNF trial Tue, Feb 25, 2020 08:00 CET. Topline analysis confirms positive safety and tolerability of CDNF in advanced-stage Parkinson’s disease patients, with encouraging biological responses as measured by PET imaging in some patients. Herantis is developing CDNF as a disease-modifying treatment with the objective of introducing a significant breakthrough to current standard-of-care therapies for Parkinson's disease.

Herantis Pharma Oyj: Herantiksen CDNF on turvallinen ja hyvin siedetty Vaiheen 1-2 tutkimuksessa 12 kuukauden hoidon jälkeen.
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The recent virtual capital markets day highlighted the progress of its two innovative assets: cerebral dopamine neurotrophic factor (CDNF), a potential disease-modifying treatment for Parkinsonâ s disease (PD); and Lymfactin, the only gene therapy in development for breast cancer Herantis Pharma is a Finnish innovative biopharmaceutical company focusing on regenerative medicines for unmet needs. Key assets include CDNF for Parkinson’s disease and Lymfactin for breast cancer associated lymphedema. 2021-03-29 · Herantis Pharma Oyj. Yhtiötiedote, Sisäpiiritieto. 29.03.2021 klo 21:00. Herantis Pharma Oyj ("Herantis" tai "Yhtiö"), innovatiivinen kliinisen vaiheen lääkekehitysyhtiö, joka kehittää uusia sairauden kulkuun vaikuttavia regeneratiivisia hoitoja, tiedotti tänään yhtiön hallituksen päättäneen keskittää Herantiksen resurssit yhtiön CDNF- ja xCDNF-ohjelmiin ja aloittaa 17 Dec 2020 "We are delighted to support Herantis Pharma in their development programs in CDNF and latest generation xCDNF molecules. Completing this Celles-ci comprennent la thérapie biologique CDNF qui agit sur les mécanismes protéostatiques de la maladie pour le traitement de la maladie de Parkinson et These include i. CDNF biological therapy that acts on the proteostatic mechanisms of disease for the treatment of Parkinson's disease and other 26 Feb 2020 Herantis Pharma Oyj. ISIN FI4000087861 2021-03-29 20:00:00 Company Announcement, Herantis Pharma keskittyy CDNF- ja xCDNF-ohjelmiin.

2018-02-14 · Herantis Pharma opening recruitment in Parkinson's disease study in Helsinki and Lund based on favorable first CDNF safety assessment. Herantis Pharma Plc Company release 14 February 2018 at 9:00 am.

This comes following Herantis' recent pivot away from direct intracerebral delivery for CDNF and towards alternative administration methods, principally intra-nasal

2014-2016 HERANTIS PHARMA Plc. All rights reserved. www.herantis.com Lymfactin® and CDNF: Aiming at breakthrough in unmet clinical needs. 1